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Also summarized are the types of low molecular weight thiols present in high concentrations in most cells, as well as the ways in which modifications of cysteinyl residues can impart or regulate molecular functions important to cellular processes including signal transduction

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The peptide's stress-protective activity extends to modulation of pro-inflammatory cytokines, with studies showing Selank effectively reduces concentrations of IL-1β, IL-6, and TGF-β1 while restoring levels of anti-inflammatory cytokine IL-4 in stressed animals