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(Patients, though, will probably pay out of pocket, as the medications won’t be FDA-approved and are unlikely to be covered by insurance.) This vertically integrated, frictionless, moneymaking process is a far cry from the backroom of a 20th-century drugstore, where a pharmacist mixed up bespoke concoctions for patients in need

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Tip geometry and gauge influence how easily the needle is placed, how clearly cerebrospinal fluid (CSF) confirms position, and how likely the patient is to develop a post-dural puncture headache (PDPH) — a complication that can extend a hospital stay or bring a discharged patient back through the door